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Biogen Scientist I / II, DMPK Bioanalytical in Cambridge, Massachusetts
About This Role Biogen is seeking a highly motivated scientist with excellent knowledge and experience in LC-MS/MS bioanalysis to join the Drug Metabolism and Pharmacokinetics (DMPK) department. The candidate will be responsible for bioanalytical support of discovery and development programs, including small molecule compounds and oligonucleotides. Experience in regulated bioanalysis and GLP studies is preferred. The candidate should be able to effectively manage and prioritize multiple projects to ensure timely support of the projects. Excellent communication and interpersonal skills are required, along with scientific thinking and problem-solving skills. * * What You’ll Do * Develop new bioanalytical methods for quantification of small molecule compounds and oligonucleotides in biological matrices. * Analyze biological samples (plasma, CSF, tissue etc.) and timely deliver high quality bioanalytical data to support non-clinical and possible clinical studies. * Oversee non-GLP and GLP bioanalytical activities at CROs. Provide scientific guidance on method transfer/development, qualification/validation, and sample analysis at CROs. * Write and review study protocols and bioanalytical reports that are suitable for inclusion in registration dossiers. * Manage multiple projects within timelines according to high scientific and ethical standards. * Evaluate and implement new bioanalytical technologies for solving DMPK challenges or project needs. * Publish scientific papers and present at external scientific meetings. Why Biogen? Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive. Required Skills * Scientist I - Ph.D. degree with 0-3 years relevant industry experience. Scientist II - Ph.D. degree with 3+ years of related industry experience. * In-depth knowledge and extensive experience with LC-MS/MS bioanalysis of small molecule compounds are required. Experience with other modalities such as oligonucleotides and proteins is desired. * Capable of performing bioanalysis and solving bioanalytical technical problems. * Familiar with bioanalytical method validation regulatory guidance and GLP regulations. * Understanding of pharmacokinetics and drug metabolism principles. * Excellent communication skills * Strong records of scientific publications * Ability to work independently in a fast-paced environment, as well as in a team setting. * Experience in ligand binding assays such as ELISA and MSD assays is a plus. All your information will be kept confidential according to EEO guidelines.