Shire Veteran Jobs

Reference #: 403658 Site Name: USA - Pennsylvania - Upper Providence Posted Date: Sep 5 2024

Are you looking to enhance your bioanalytical expertise by working for a global pharmaceutical company that allows you to leverage best in class LC-MS systems and technologies?  If so, this Principal Scientist role is the ideal opportunity for you.  At our world-class scientific hub in Upper Providence, Pennsylvania, our Biomarker and Bioanalytical Platforms (BBP) department currently has an exciting career opportunity for a talented individual with a passion for the analytical sciences and applying their skill set to addressing human disease.

As a Principal Scientist within the LC-MS Bioanalysis group, you will be responsible for the development and validation of assays to deliver PK and PD endpoints for clinical studies across the GSK portfolio.  Data from this group is a key component to understanding molecules in the GSK pipeline and serves to make early and informed decisions for asset progression within the organization.

This role will provide you the opportunity to lead key activities to progress your career, these responsibilities include some of the following:

Responsible for developing LC-MS based bioanalytical assays to support clinical studies, delivery of robust, high-quality data packages.

Deliver, interpret, and communicate complex scientific data to project/program teams in a timely manner by performing data analysis, record keeping and reporting of results to agreed timelines.

Drive the implementation of novel LC-MS based bioanalytical strategies for the measurement and characterization of drug, metabolites, and biomarkers in biological samples.

Contribute to departmental strategy and capital investment discussions.

Act as a Bioanalytical Subject Matter Expert for clinical study teams.

Handling of human biological samples and performing experimental work in accordance with HBSM, safety and data integrity guidelines.

Contribute to the development of innovative LC/MS platforms internally and externally through conferences, publications, and working groups.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

BS in Chemistry, Biochemistry or related discipline with 10 or more years of pharmaceutical industry bioanalysis experience

Experience with development of mass spectrometry-based methods to measure analytes from biological matrices.

Experience troubleshooting methodological issues.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

PhD in Chemistry, Biochemistry or related discipline.

MS in Chemistry, Biochemistry or related discipline with 5 or more years of pharmaceutical industry bioanalysis experience.

Excellent computer skills for communication and report writing.

Experience with analysis and reporting of preclinical or clinical PK data.

Understanding of regulatory requirements for GxP analytical activities.

Experience utilizing laboratory information management systems for daily job functions.

Highly motivated team player with a proactive attitude, excellent organizational skills and a demonstrated ability to interact effectively within a multi-disciplinary team.

Strong record of publications and presentations in novel biological or analytical mass spectrometry methods and applications

#LI-GSK Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK? Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccine , specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.