Shire Cluster Operations Lead - UK & Ireland in Paddington, United Kingdom

JOB TITLE: Cluster Operations Lead - UK & Ireland

JOB LOCATION: Paddington, UK

JOB DETAILS: Permanent, Full-time position


The Cluster Operations Lead will manage the Supply Chain systems and processes for the cluster, reporting to the Head of the Cluster Supply Chain.

The individual will be responsible for ensuring all relevant Supply Chain systems and processes are appropriately developed, maintained and improved, including demand forecasting, supply of product to the markets, new product launch, recalls, management of customers, customer complaints, order processing, inventory management & reconciliation, and day to day management of 3PL & Customs agents.

This individual will be responsible for communicating Supply and Demand information to Supply Chain in a timely manner and liaising appropriately with QA, Regulatory Affairs, Commercial and other relevant functions to resolve supply issues.

The Cluster Operations Lead will manage Supply Chain audit readiness for the cluster in coordination with Quality and Finance.

This individual will be responsible for the timely completion of goals and objectives.


40% of the time; Product Supply/ Logistics

  • Working with the Regional/Cluster Supply Chain leaders to ensure reliable supply of Product to Customer and Patient

  • Manage Demand Forecast process for Cluster and drive S&OP process for the cluster

  • Work with Global Supply Chain to ensure uninterrupted supply of product to Cluster inventory

  • Manage local inventories and liaise with production/distribution planning

  • Monitor performance and manage the daily operations with the local logistics partner

  • Team member in launch execution teams representing Cluster to manage launch of new products.

  • Support Cluster input to Tender Management.

40% of the time; Continuous Improvement / Process and Systems

  • Regional/Cluster lead for new system and process implementation

  • Assemble/lead cross functional teams/sub-teams to resolve systemic and systematic network issues across various areas of technical and life cycle complexity that ultimately support product in the market where poor decisions impact brand availability and Shire sales.

  • Lead projects in support of continuous improvement of systems and processes

20% of the time; Customer Support

  • Manage Customer Support systems to ensure availability and reliability.

  • Manage Regional/Cluster Logistics processes in support of reliable supply of product to Customer and Patient

  • Manage Internal and External Reporting as required to support compliant reliable supply of product to Customer and Patient

  • Manage interface with key Distribution partners.



  • Bachelor Degree in business, Supply Chain or equivalent

  • At least 7 years of progressive experience in various supply chain management roles within the Pharmaceutical or Healthcare industries


  • Knowledge of ERP systems including packages relating to supply chain mgmt.


Living our leadership behaviors is a basic expectation for all Shire employees. Shire expects all employees to embody the following:

Leadership Behaviors

  • Be Positive

  • Be Accountable

  • Be Results Oriented

  • Be An Excellent Manager of Self

  • Provide open and collaborative ways of working to support various functional and/or departmental initiatives evaluating major issues and removing or reducing the risk from obstacles/variables that may arise.

  • Impact through successful leadership and development of plans based on a sound understanding of the external market, internal requirements and the ability to determine and then leverage the market place.

  • Support implementation of Continuous Improvement initiatives (including Lean Sigma/Operational Excellence)

  • Ability to think “outside the box” and be well versed in the global distribution

  • Knowledge of different aspects of regulatory compliance that impact a pharmaceutical supply chain. This can include but is not limited to GxP considerations and controlled substance regulations

  • Able to recognize the importance of meeting business needs and balance cost, quality and customer service

  • Effective written and oral communication skills are required to facilitate information flow across internal / external supply chain partners and senior leadership.

  • Must be able to demonstrate leadership ability in driving change within an organization. This could include systems, processes or tools to drive success


  • Professional relationship building that influences and advances business priorities on wide ranging aspects and issues in a complex supply and distribution environment that may impact peer groups Commercial, Tech Ops or other functions.

  • Ability to manage the day to day Supply Chain Operations for the Region/Cluster; and meet simultaneously, the Region/Cluster, Business Unit, Commercial and Tech Ops goals. Specific challenges and complexities revolve around balancing service, schedule compliance, productivity / cost objectives due to constraints, QA issues, change controls, projects, etc.

  • Balance the requirements of Compliance (Corporate, Financial, Quality, Taxation and Global Trade) to achieve a sustainable and scalable operation.

  • Systems, policies and procedure design in light of resources and agreements across numerous functions.

  • Deal with ambiguity resulting in a high degree of risk management and appropriate risk mitigation

  • Deal with a wide range of problems (Launch, Integration, New Market Entry) that require complex judgments and innovative solutions in order to meet the needs of the BUs, Commercial and Tech Ops.


Primary Internal Contacts: Primary External Contacts:

  • There is significant contact with many different functions within Shire. The Cluster Operations Lead will be required to manage several different requirements at one given time and will specifically have to align on critical timelines with Shire IT, Finance and other functional Tech Ops leads (i..e Planning, Quality, Logistics) to ensure business activities are being managed accordingly

  • Externally, significant interaction will occur with 3PLs, Shire employed IT consultants, local suppliers (if relevant) and other Service Suppliers. The management of external contacts will require strong influential skills due to a strong need for all external contacts to be fully engaged and bought into the process.

  • Excellent communication skills including presenting to individuals at different seniority levels are a must. The Cluster Operations Lead will be asked to prepare and present solutions to all contacts and senior management team members.


  • This position will include international travel on an occasional basis to ensure the systems and processes are integrated or implemented

Notice to Employment / Recruitment Agents:

Employment / Recruitment agents may only submit candidates for vacancies only if they have written authorization to do so from Shire’s Talent Acquisition department. Any agency candidate submission may only be submitted to positions opened to the agency through the specific Agency Portal. Shire will only pay a fee for candidates submitted or presented where there is a fully executed contract in place between the Employment / Recruitment agents and Shire and only if the candidate is submitted via the Agency Portal. Candidates submitted or presented by Employment / Recruitment Agents without a fully executed contract or submitted through this site shall not be deemed to form part of any Engagement for which the Agency may claim remuneration.

Shire is the leading global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. We strive to develop best-in-class products, many of which are available in more than 100 countries, across core therapeutic areas including Hematology, Immunology, Neuroscience, Ophthalmics, Lysosomal Storage Disorders, Gastrointestinal/Internal Medicine/Endocrine and Hereditary Angioedema; and a growing franchise in Oncology.

Our employees come to work every day with a shared mission: to develop and deliver breakthrough therapies for the hundreds of millions of people in the world affected by rare diseases and other high-need conditions, and who lack effective therapies to live their lives to the fullest.