Responsibilities:
There is strong evidence that underrepresentation is an important problem that the health research enterprise must address (see). Fostering diversity by addressing underrepresentation in the research workforce is consistent with Seattle Children's.
A fully supported Postdoctoral Scholar position is available in the *Seattle Tuberculosis Research Advancement Centers (SEATRAC) to characterize immune response of novel vaccines and immune pathology associated with tuberculosis and co-morbidities. Previous experience in cellular immunology, including multiparametric flow cytometry, is required. This Postdoctoral position provides the time, funding, mentorship, experiences and training necessary to foster the early career development of the next generation of researchers.
The postdoctoral fellow will receive funding, focused mentoring, experience and training in laboratory and clinical settings and will develop expertise in the assessment of vaccine mediated immune responses and systems immunology. A key aspect will include combining information from multiple levels such as genes, proteins and whole cells to gain a clear, multi-scale understanding of vaccine function during infection and disease. The fellowship is designed to prepare the postdoctoral level trainee for a career in a non-profit biotechnology- and multidisciplinary setting. The objective of this postdoctoral position at Seattle Children's Research Institute is to support promising researchers from backgrounds recognized as Underrepresented in the Extramural Scientific Workforce.
Qualifications:
A PhD with related laboratory experience in Immunology, Microbiology, Cellular & Molecular Biology or similar
Experience and skills in cellular immunology and T- and B-cell based assays (e.g., >10-color flow cytometry panels, B cell ELISpot (ASC), T cell cytokine ELISpot, ADCC, cytokine multiplex assays)
Deep understanding of immunology and/or human biomarker research
Proficiency in MS Office, scientific data/graphics programs, flow cytometry software, and biostatistics
A strong track record of publication
Experience working under Biosafety Level 2 or 3 (BL2/BL3) conditions
Willingness and ability to work under BL3 conditions with appropriate training
Experience working with small animal models of infectious diseases
Excellent oral and written communication skills in English
Must be self-motivated, highly organized and be able to work on teams
Primary Responsibilities:
Assessment of cellular, molecular and computational immunological endpoints in preclinical projects
Contribute to study reports, statistical analysis plans and grant applications
Work closely under supervision to implement research projects that further the understanding and development of effective vaccines
Committed participation as a team member to support experimental design, developing immunoassay methodology following scientific literature review, quality standards and discussion with peers, as required
Responsible for following Standard Operating Procedures
Records procedures, outcomes and observations in lab notebook following established guidelines
Utilize established mathematical and scientific techniques to compile, critically analyze and interpret data
Communicate with research management on a regular basis
Prepare manuscripts for publication in peer reviewed journals
Presents research at group and internal/external scientific meetings
Knowledge, Skills and Abilities:
Work as a member of a collaborative team under general supervision
Able to use experience and judgment to plan and accomplish goals
Able to perform multiple scientific protocols and procedures
Good written and oral communication skills; ability to communicate tactfully and effectively
Experience writing manuscripts and grants helpful
Ability to work accurately with close attention to