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Merck Scientist, High-Throughput Purification in South San Francisco, California

Job Description

The successful candidate will be a self-starter and detail-oriented, with an analytical mindset and thrives in a fast-paced, collaborative team environment. The candidate will be responsible for developing chromatographic methods and provide routine and specialized purification support and reporting for a range of modalities at varying scales, leveraging a variety of analytical techniques, novel instrumentation, and custom informatics tools. Specific responsibilities will include:

Job responsibilities include:

  • Being an integral part of our company's growing High-Throughput Purification team and work with chemists, biologists, and engineers to advance our drug discovery pipeline

  • Operating state of the art analytical and purification instrumentation (HPLC, UPLC, SFC, Hi-Res MS, 2D-LC) to characterize and purify lead candidates from small molecules to peptides and bioconjugates

  • Developing specialty separations, and optimize related chromatographic methods for individual programs

  • Identifying, evaluating, and recommending novel instrumentation and workflows to achieve early-stage project goals

  • Collaborating with automation teams to design and implement machine learning software tools and robotics to automate laboratory workflows and processes

  • Overseeing overall instrument performance and health, performing basic troubleshooting, and schedule preventative maintenance and repair with key vendors

  • Contributing to our external scientific presence through presentations and the writing of technical documents, scientific manuscripts, etc.

Position Qualifications:

Education:

  • Bachelor's degree in Analytical Chemistry, Chemical Engineering, Biochemistry or related field with three (3) years of relevant experience

  • Master's degree in Analytical Chemistry, Chemical Engineering, Biochemistry or related field with zero (0) years of relevant experience

Required Experience and Skills:

  • Hands-on research experience with HPLC techniques, LC-MS, and/or assay development

  • Demonstrated ability to independently develop and perform critical experiments in a fast-paced, dynamic environment

  • Self-motivated with high attention to detail, ability to rapidly analyze, summarize and present data and significant conclusions

  • Excellent organizational skills with ability to meet deadlines and prioritize work on multiple projects

  • Uncompromising integrity and proven success working in a high-performing, diverse, and inclusive team environment

  • Ability to communicate clearly and build collaborative relationships

Preferred Experience and Skills:

  • Familiarity with Waters, ThermoFisher, and/or Agilent LC-MS instrumentation, relevant software platforms, subsequent data analyses and interpretation

  • Experience in programing and operating automated liquid handling systems and centrifugal evaporators

  • Prior exposure to high-throughput lab operations, automation, method development, and compound array purification

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE (https://wd5.myworkday.com/msd/d/task/1422$6687.htmld)

Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld)

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088_EEOC_KnowYourRights_10_20.pdf)

EEOC GINA Supplement​

Pay Transparency Nondiscrimination (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp_%20English_formattedESQA508c.pdf)

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/)

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

Under New York State, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

Expected salary range:

$102,800.00 - $161,900.00

Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here (https://www.benefitsatmerck.com/) .

Search Firm Representatives Please Read Carefully

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

1st - Day

Valid Driving License:

No

Hazardous Material(s):

YES

Job Posting End Date: 05/31/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID: R291239

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